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Balanced intestinal flora

The intestinal flora is made up of different species of beneficial bacteria, that colonise intestinal mucosa, living in symbiosis with the organism.

The intestinal flora contains beneficial, "friendly" bacteria and also harmful, “bad” bacteria. In a healthy organism the proportion of “good” bacteria should be 85% against 15% of “bad” bacteria”1.


The role of probiotics in the organism2

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    They can reduce the occurrence of diarrhea produced by antibiotherapy

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    They can reduce the duration and severity of infectious diarrhea

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    They can reduce the occurrence of atopic dermatitis in children at risk

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    They can reduce the severity of pain and meteorism from Irritable Bowel Syndrome

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    They may be useful in treating Helicobacter Pylori infection

During the lifetime, our intestinal flora changes depending on many factors. Stress, lifestyle, diet, hygiene, but especially all treatments with antibiotics can affect the intestinal flora on the long term.

When fighting infections, antibiotics destroy bad bacteria getting the victory, but as a result of the victorious fight of the antibiotics, good bacteria are also affected, and our intestinal flora is unbalanced.

A single oral treatment with antibiotics destroys the composition and diversity of intestinal flora for months and even up to one year in many cases. The intestinal flora imbalance involves symptoms such as bloating, abdominal discomfort, growling stomach and even diarrhea.3

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When is it advisable to take probiotics?


butterflyFollowing treatment with oral antibiotics

Use of antibiotics is common in children. Studies have shown that almost 20% of the children in treatment with antibiotics have developed diarrhea. The American Academy of Paediatrics recommends the use of probiotics for the prevention of antibiotic-associated diarrhea.4

All studies have shown that probiotics associated with antibiotherapy have protective effect in antibiotic-associated diarrhea. The most conclusive results were obtained with strains of Lactobacillus Rhamnosus GG and Saccharomyces Boulardii. Hepiflor sachets contains Lactobacillus Rhamnosus strains.

In adults, the incidence of antibiotic-associated diarrhea is reported in 5 to 25% of patients.5

This rate has increased in recent years, even with an incidence of 30% reported in some cases.6

A solution for restoring the intestinal flora affected by antibiotics and reducing the occurrence of diarrhea associated with antibiotic treatment, would be to associate a probiotic in order to balance the created imbalance.

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butterfly Following food poisoning - in infections of the intestinal tract

Probiotics are recommended to restore the balance of intestinal flora in the case of food poisoning, infectious diarrhea, as treatment associated with the main treatment.

butterfly In the treatment of Irritable Bowel Syndrome

Probiotics are also recommended in case of abdominal discomfort in patients with Irritable Bowel Syndrome, intestinal functional disorders, intestinal dyspepsia, with symptoms such as:

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    Constipation alternating with diarrhea

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    Abdominal discomfort

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    Growling stomach

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    In association with the background treatment - main treatment.

1. Holzapfel WH, Haberer P et al.” Overview of gut flora and probiotics”.Int J of Food Microbiol 1998; 41:85-101

2. American Family Physician, 2008, 78(9), 1073-78


4. Clin Gastroenterol Hepatol 2012 September

5. World J Gastroenterol 2014 December 21; 20(47)

6. J.Winstron, S.Ragner, frequency of antibiotic- associated diarrhea in 2462 antibiotic treated patients, Journal of Antimicrobial Chemotherapy 2001.